Rat-bite fever septic arthritis: illustrative case and literature review

  title={Rat-bite fever septic arthritis: illustrative case and literature review},
  author={Claire Dendle and Ian J Woolley and Tony M. Korman},
  journal={European Journal of Clinical Microbiology and Infectious Diseases},
  • C. Dendle, I. Woolley, T. Korman
  • Published 10 November 2006
  • Medicine, Biology
  • European Journal of Clinical Microbiology and Infectious Diseases
Rat-bite fever is a rare zoonotic infection caused by Streptobacillus moniliformis or Spirillum minus, which is characterised by fever, rash and arthritis. The arthritis has previously been described as non-suppurative and isolation of the organism from synovial fluid as very uncommon. This article reports a case of septic arthritis diagnosed as rat-bite fever when the organism was cultured from synovial fluid and reviews another 15 cases of S. moniliformis septic arthritis reported in the… 
Surgical Management of Multijoint Septic Arthritis due to Rat-Bite Fever in a Pediatric Patient: A Case Study
A pediatric case of delayed onset septic arthritis in the left wrist and right knee due to S. moniliformis from a rat bite is reported, demonstrating the importance of a thorough exposure history and consideration of zoonotic infections as a cause of septicthritis in a pediatric patient that requires antibiotics and surgical intervention.
Streptobacillus moniliformis bacteremia in a rheumatoid arthritis patient without a rat bite: a case report
It is concluded that S. moniliformis infection can become established with contaminated vehicle contact alone, not only as a direct result of a bite, and those working in places where rodents breed or are at risk of contact with rats or mice might be at risk for contracting this unusual disease.
Erosive polyarthritis caused by sepsis due to a novel species of Streptobacillus notomytis
It is essential to consider Streptobacillus infection in the differential diagnosis of erosive polyarthritis, and a novel species isolated from S. moniliformis is presented, causing septic arthritis in a 67-year-old man presented with fever, purpura and peripheral arthritis.
Rat-Bite Fever Due to Streptobacillus moniliformis
A case series and literature review of rat-bite fever describe a characteristic clinical picture with fever, arthritis, and rash; a history of rat exposure is supportive, and blood cultures with current laboratory techniques are usually diagnostic.
Rat Bite Fever, a Fatal Case of Streptobacillus moniliformis Infection in a 14‐Month‐Old Boy
This case highlighted key features, such as the morbiliform rash, but lacked lymphadenopathy or joint manifestations, so it is important to consider rat or rodent exposure as a source of infection.
Toe Gangrene Revealing Septicaemical Rat-bite Fever: About a 41 Day Old Infant
The case of a 41-day-old female infant who was the victim of a rat bite at one month of life in the upper nasal and labial areas is reported, with the diagnosis of rat bite fever having been retained.
Rat Bite Fever: A Case Report and Review of the Literature.
A case of a 17-year-old girl who presented with S moniliformis bacteremia and symptoms that spanned both RBF and S monILiformis septic arthritis is reported, emphasizing the difficulty in differentiating the 2 clinical entities and the importance of early diagnosis, proper clinical suspicion, and prompt treatment to achieve positive outcomes.
A Case of Rat Bite Fever Arthritis
A patient who developed arthritis with fever after biting by rat is reported, and the response to antibiotic treatment is good and early diagnosis is the most important prognostic factor.
Rat Bite Fever Resembling Rheumatoid Arthritis
A case of culture-positive rat bite fever is reported in a 46-year-old female presenting with fever and polyarthritis, which mimicked rheumatoid arthritis, and the diagnosis and management are discussed.
A case of shoulder joint Streptobacillus moniliformis septic arthritis with severe subdeltoid bursitis
In a recent case of septic shoulder arthritis and severe subdeltoid bursitis due to rat-bite fever in a 19-year-old female, pre-operative magnetic resonance imaging scans demonstrated severe bursal involvement.


Septic Arthritis of the Hip Secondary to Rat Bite Fever: A Case Report
The orthopaedist should be aware of not only Streptobacillus moniliformis, but also of other zoonotic organisms, which potentially can cause septic arthritis and warrant treatment with specific antibiotics.
Rat-bite fever as a cause of septic arthritis: a diagnostic dilemma.
A patient with rat-bite fever resulting in suppurative arthritis is described, which was delayed, owing to the lack of an exposure history, atypical clinical presentation, and the unusual microbiologic characteristics shown by this organism.
A case of streptobacillary-ratbite fever successfully treated with penicillin is reported, and the therapeutic programs used have been compared with the results achieved in an attempt to determine optimal management with antimicrobials now available.
Streptobacillary fever. An unusual cause of infectious arthritis.
  • D. Mandel
  • Medicine
    Cleveland Clinic quarterly
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This case report demonstrates the rare occurrence of rat-bite fever manifested by septic arthritis successfully treated with penicillin.
[Arthritis caused by Streptobacillus moniliformis: a case of fever induced by a rat bite].
A 54-year-old female had fever with chills, polyarthritis and diffuse rash, which led to the suspicion of rat-bite fever, the first case of that condition reported in this country.
Rat bite fever without fever
Diagnosis has important prognostic implications as the disease is potentially lethal, but easily treatable, as in the present case.
Fatal rat-bite fever--Florida and Washington, 2003.
  • Medicine, Biology
    MMWR. Morbidity and mortality weekly report
  • 2005
Two rapidly fatal cases of RBF identified by the CDC Unexplained Deaths and Critical Illnesses (UNEX) Project in 2003 underscore the importance of including RBF in the differential diagnoses of acutely ill patients with reported rat exposures and preventing zoonotic infections among persons with occupational or recreational exposure to rats.
A rare and serious consequence of a rat bite.
A case of septic arthritis of the hip due to S. moniliformis is reported following a bite on the finger of a 14-year-old boy from a rat for sale in a pet shop, highlighting a possible danger of keeping rats as pets.
Rat-bite fever (Streptobacillus moniliformis): a potential emerging disease.
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  • Medicine, Biology
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