Rat Brain-Uptake Index for Phenylethylamine and Various Monomethylated Derivatives

@article{Mosnaim2013RatBI,
  title={Rat Brain-Uptake Index for Phenylethylamine and Various Monomethylated Derivatives},
  author={Aron David Mosnaim and Owen H. Callaghan and Thomas J Hudzik and Marion E. Wolf},
  journal={Neurochemical Research},
  year={2013},
  volume={38},
  pages={842-846}
}
Phenylethylamine and its monomethylated derivatives p-methylphenylethylamine, α-methylphenylethylamine, phenylethylamine itself, N-methylphenylethylamine, o-methylphenylethylamine, and β-methylphenylethylamine, readily cross the blood-brain barrier showing a brain-uptake index (%) ± SD (water considered 100 %), of 108 ± 11, 98 ± 14, 83 ± 6, 78 ± 11, 62 ± 7 and 56 ± 6, respectively (injection of tritiated water and 100 μg standard amine, which was measured by gas-liquid chromatography). Similar… 
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