Rasburicase improves hyperuricemia in patients with acute kidney injury secondary to rhabdomyolysis caused by ecstasy intoxication and exertional heat stroke

  title={Rasburicase improves hyperuricemia in patients with acute kidney injury secondary to rhabdomyolysis caused by ecstasy intoxication and exertional heat stroke},
  author={Pei-Yi Lin and Chun-Chen Lin and Hsi-Che Liu and Ming-Dar Lee and Hung-Chang Lee and Che-Sheng Ho and Nan-Chang Chiu and Chun-Chih Peng and Fu-yuan Huang and J D Tsai},
  journal={Pediatric Critical Care Medicine},
Objective: To report the successful use of rasburicase in two children with hyperuricemia secondary to severe rhabdomyolysis. Design: Case report. Setting: Pediatric intensive care unit in a freestanding quaternary hospital. Patients: Two pediatric patients with severe rhabdomyolysis and hyperuricemia caused by ecstasy intoxication and exertional heat stroke. Intervention: Use of a single low dose (6 mg) of rasburicase, a urate oxidase enzyme. Measurements and Main Results: Rasburicase was… 

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