Rasagiline interferes with neurodegeneration in the Prph2/rds mouse.

Abstract

PURPOSE Rasagiline (N-propargyl-1(R)-aminoindan) is a second-generation propargylamine with neuroprotective effects. We used the Prph2/rds mouse to assess the effect of rasagiline on photoreceptor cell death and to examine the possible modulation of different pathways of programmed cell death. METHODS The animals were orally treated with various doses of… (More)
DOI: 10.1097/IAE.0b013e31821e2070

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