Ras caught in another affair: the exchange factors for Ral.

@article{Wolthuis1999RasCI,
  title={Ras caught in another affair: the exchange factors for Ral.},
  author={Rob M. F. Wolthuis and J. L. Bos},
  journal={Current opinion in genetics & development},
  year={1999},
  volume={9 1},
  pages={
          112-7
        }
}
The Ral guanine nucleotide exchange factors are direct targets of Ras, providing a mechanism for Ral activation by extracellular signals. In addition, Ral can be activated by a Ras-independent pathway. Ral guanine nucleotide exchange factors contribute to cellular transformation induced by oncogenic Ras through an Erk-independent mechanism which may involve activation of transcription. 

Topics from this paper.

Citations

Publications citing this paper.
SHOWING 1-10 OF 62 CITATIONS, ESTIMATED 58% COVERAGE

SELECTIVE REGULATION OF CARDIOMYOCYTE SIGNALING BY RGL2

VIEW 4 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

Activating proto-oncogene mutations in human cutaneous melanoma

VIEW 6 EXCERPTS
CITES BACKGROUND
HIGHLY INFLUENCED

FILTER CITATIONS BY YEAR

2000
2018

CITATION STATISTICS

  • 5 Highly Influenced Citations