Rare and Common Variants Conferring Risk of Tooth Agenesis.

@article{Jonsson2018RareAC,
  title={Rare and Common Variants Conferring Risk of Tooth Agenesis.},
  author={L Jonsson and Thomas Magnusson and A Thordarson and Thorvaldur Jonsson and Frank Geller and Bjarke Feenstra and Mads Melbye and Ellen A Nohr and Strahinja Vucic and Brunilda Dhamo and Fernando Rivadeneira and Edwin M Ongkosuwito and Eppo Bonne Wolvius and Elizabeth J. Leslie and Mary L. Marazita and Brian J Howe and Lina M. Moreno Uribe and Isabel Alonso and Madalena Santos and Teresa Pinho and Roland Jonsson and G Audolfsson and L{\'a}rus J. Gudmundsson and Md. Sharfaraj Nawaz and Sigurgeir Olafsson and {\'O}mar G{\'u}stafsson and Andr{\'e}s Ingason and Unnur Unnsteinsdottir and Gyda Bjornsdottir and G Bragi Walters and Mark Zervas and Asmundur Oddsson and Daniel Fannar Gudbjartsson and Stacy Steinberg and Hreinn Stef{\'a}nsson and K{\'a}ri Stef{\'a}nsson},
  journal={Journal of dental research},
  year={2018},
  volume={97 5},
  pages={
          515-522
        }
}
We present association results from a large genome-wide association study of tooth agenesis (TA) as well as selective TA, including 1,944 subjects with congenitally missing teeth, excluding third molars, and 338,554 controls, all of European ancestry. We also tested the association of previously identified risk variants, for timing of tooth eruption and orofacial clefts, with TA. We report associations between TA and 9 novel risk variants. Five of these variants associate with selective TA… CONTINUE READING

Figures, Tables, and Topics from this paper.

Citations

Publications citing this paper.

References

Publications referenced by this paper.
SHOWING 1-10 OF 41 REFERENCES

Prevalence of dental anomalies in children with cleft lip and unilateral and bilateral cleft lip and palate

R Rullo, VM Festa, +3 authors L. Perillo
  • Eur J Paediatr Dent. 16(3):229–232.
  • 2015
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Spectrum of Dental Phenotypes in Nonsyndromic Orofacial Clefting.

  • Journal of dental research
  • 2015
VIEW 8 EXCERPTS
HIGHLY INFLUENTIAL

Molecular patterning of the mammalian dentition.

  • Seminars in cell & developmental biology
  • 2014
VIEW 6 EXCERPTS
HIGHLY INFLUENTIAL

Analysis of protein-coding genetic variation in 60,706 humans

M Lek, KJ Karczewski, +7 authors BB Cummings
  • Nature
  • 2016
VIEW 3 EXCERPTS
HIGHLY INFLUENTIAL

Similar Papers

Loading similar papers…