Rapidly progressive aphasia and motor neuron disease: a clinical, radiological, and pathological study of an autopsy case with circumscribed lobar atrophy

@article{Tsuchiya2000RapidlyPA,
  title={Rapidly progressive aphasia and motor neuron disease: a clinical, radiological, and pathological study of an autopsy case with circumscribed lobar atrophy},
  author={Kuniaki Tsuchiya and Eijiro Ozawa and Junko Fukushima and Hiroshi Yasui and Hiroshi Kondo and Imaharu Nakano and Kenji Ikeda},
  journal={Acta Neuropathologica},
  year={2000},
  volume={99},
  pages={81-87}
}
This report concerns an autopsy case of rapidly progressive aphasia and motor neuron disease. The patient was a Japanese woman who was 75 years old at the time of death. The family history did not reveal hereditary burden. She developed language disturbances and difficulty in swallowing at age 74. Neurological examination 1 month after the disease onset revealed motor aphasia without dementia and bulbar sign, followed by muscle weakness of the four extremities. Neuroradiological examination… CONTINUE READING
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