Rapidly in situ forming chitosan/ε-polylysine hydrogels for adhesive sealants and hemostatic materials.

@article{Nie2013RapidlyIS,
  title={Rapidly in situ forming chitosan/ε-polylysine hydrogels for adhesive sealants and hemostatic materials.},
  author={Wei Nie and Xiaoyan Yuan and Jin Zhao and Yalin Zhou and Huijing Bao},
  journal={Carbohydrate polymers},
  year={2013},
  volume={96 1},
  pages={
          342-8
        }
}
A novel in situ forming polysaccharides/polypeptide hydrogel composed of naturally derived materials for applications as adhesive sealant and hemostatic material was developed via Michael addition crosslinking, taking advantage of its mild condition. Thiol-modified chitosan (CSS) was fast in situ crosslinked by an efficient polypeptide crosslinker (EPLM) which was prepared by introducing maleimide groups onto ε-polylysine. Gelation can happen swiftly within 15-215s depending on the CSS… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 36 REFERENCES

Formulation and characterization of poloxamine - based hydrogels as tissue sealants

E. ho, J. S. Lee, K. Webb
  • Acta Biomaterialia
  • 2012