Rapid upregulation of sodium-glucose transporter SGLT1 in response to intestinal sweet taste stimulation.

@article{Stearns2010RapidUO,
  title={Rapid upregulation of sodium-glucose transporter SGLT1 in response to intestinal sweet taste stimulation.},
  author={Adam T. Stearns and Anita Balakrishnan and David B. Rhoads and Ali Tavakkolizadeh},
  journal={Annals of surgery},
  year={2010},
  volume={251 5},
  pages={
          865-71
        }
}
OBJECTIVE We set out to examine the short-term regulation of the intestinal sodium/glucose cotransporter SGLT1 by its substrate glucose and sweet taste analogs. SUMMARY BACKGROUND DATA Intestinal SGLT1 is a putative target for antidiabetic therapy; however, its physiological regulation is incompletely understood, limiting its application as a pharmacological target. While it is clearly regulated by dietary composition over a period of days, its short-term regulation by nutrients is unknown… CONTINUE READING
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Localized glucose and water influx Stearns et al Annals of Surgery

XM Chen, SP O’Hara, BQ Huang
  • Volume 251, Number
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