Rapid titration versus conventional titration of quetiapine in the treatment of bipolar mania: a preliminary trial.

@article{Pae2005RapidTV,
  title={Rapid titration versus conventional titration of quetiapine in the treatment of bipolar mania: a preliminary trial.},
  author={Chi-Un Pae and S Nassir Ghaemi and Tae-Suk Kim and Jung-Jin Kim and Soo-Jung Lee and C Lee and Chul Hyun Lee and In-Ho Paik},
  journal={International clinical psychopharmacology},
  year={2005},
  volume={20 6},
  pages={327-30}
}
The present trial was designed as a pilot study to re-examine how fast the dose of quetiapine in combination with mood stabilizers can be titrated upward in acutely ill patients with bipolar mania. Patients were assigned to either a rapid titration group (RTG) or a conventional titration group (CTG). Quetiapine was administered twice daily in a 3-day period in the RTG (200 mg/day on day 1; 400 mg/day on day 2; and 600 mg/day on day 3) and in a 5-day period in the CTG (50 mg/day on day 1; 100 mg… CONTINUE READING