Rapid testing leads to the underestimation of the scrapie prevalence in an affected sheep and goat flock.

@article{Reckzeh2007RapidTL,
  title={Rapid testing leads to the underestimation of the scrapie prevalence in an affected sheep and goat flock.},
  author={Claudia Reckzeh and Christine Hoffmann and Anne Buschmann and S Buda and K. -D. Budras and Karl-Friedrich Reckling and Steffi Bellmann and H. Sophie Knobloch and Georg Erhardt and Reinhard Fries and Martin H Groschup},
  journal={Veterinary microbiology},
  year={2007},
  volume={123 4},
  pages={320-7}
}
To obtain a more detailed understanding of the prevalence of classical scrapie infections in a heavily affected German sheep flock (composed of 603 sheep and 6 goats), we analysed 169 sheep and 6 goats that carried the genotypes susceptible to the disease and that were therefore culled following discovery of the index case. The initial tests were performed using the Biorad TeSeE ELISA and reactive results were verified by official confirmatory methods (OIE-immunoblot and/or immunohistochemistry… CONTINUE READING