Rapid suppression of complex ventricular arrhythmias with high-dose oral amiodarone.

@article{Mostow1986RapidSO,
  title={Rapid suppression of complex ventricular arrhythmias with high-dose oral amiodarone.},
  author={N D Mostow and Thomas R Vrobel and D L Noon and L G Rakita},
  journal={Circulation},
  year={1986},
  volume={73 6},
  pages={1231-8}
}
Although amiodarone is effective for the suppression of complex ventricular arrhythmias, a major problem with its use is the long delay between the initiation of therapy and the onset of effective suppression of arrhythmia. To test the hypothesis that rapid loading with oral amiodarone to a target serum concentration can overcome much of this delay, eight patients with refractory, sustained, hemodynamically compromising ventricular arrhythmias and 10 patients with potentially life-threatening… CONTINUE READING