Rapid selection of drug-resistant HIV-1 during the first months of suppressive ART in treatment-naive patients.

@article{Metzner2007RapidSO,
  title={Rapid selection of drug-resistant HIV-1 during the first months of suppressive ART in treatment-naive patients.},
  author={Karin J. Metzner and Kristina Allers and Pia Rauch and Thomas Harrer},
  journal={AIDS},
  year={2007},
  volume={21 6},
  pages={703-11}
}
OBJECTIVE Efficient antiretroviral therapy (ART) of HIV-1 infection reduces the viral load to undetectable levels and restores the immune system. However, therapy failure appears in a substantial fraction of patients and is mostly associated with the appearance of drug-resistant viruses. It is still not clear when the drug pressure leads to the earliest selection and appearance of drug-resistant HIV-1 populations. In this study, we wanted to determine whether drug-resistant viruses are already… CONTINUE READING

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