Rapid screening of antibiotic toxicity in an automated microdroplet system.


We report an automated microfluidic platform for 'digitally' screening the composition space of droplets containing cocktails of small molecules and demonstrate the features of this system by studying epistatic interactions between antibiotics and Escherichia coli ATCC 25922. This system has several key characteristics: (i) it uses small (<100 μL) samples… (More)
DOI: 10.1039/c2lc21284f


1 Figure or Table