Rapid screening for 67 drugs and metabolites in serum or plasma by accurate-mass LC-TOF-MS.

@article{Marin2012RapidSF,
  title={Rapid screening for 67 drugs and metabolites in serum or plasma by accurate-mass LC-TOF-MS.},
  author={Stephanie J. Marin and John M. Hughes and Bryan G Lawlor and Chantry J Clark and Gwendolyn A. McMillin},
  journal={Journal of analytical toxicology},
  year={2012},
  volume={36 7},
  pages={477-86}
}
Sixty-seven drugs and metabolites were detected in serum or plasma using a fast (7.5 min) liquid chromatography time-of-flight mass spectrometry (LC-TOF-MS) method. This method was developed as a blood drug screen, with emphasis on the detection of common drugs of abuse and drugs used to manage chronic pain. Qualitative drug detection may identify a drug exposure, assure patient adherence with prescribed therapy and document abstinence from non-prescribed medications. Compound identification is… CONTINUE READING

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