Rapid reversible modulation of human motor outputs after transient deafferentation of the forearm: a study with transcranial magnetic stimulation.

@article{BrasilNeto1992RapidRM,
  title={Rapid reversible modulation of human motor outputs after transient deafferentation of the forearm: a study with transcranial magnetic stimulation.},
  author={Joaquim Pereira Brasil-Neto and Leonardo G. Cohen and Alvaro Pascual-Leone and F K Jabir and Ray Wall and Mark Hallett},
  journal={Neurology},
  year={1992},
  volume={42 7},
  pages={1302-6}
}
Reorganization of corticospinal pathways after spinal cord injury and amputations leads to increased excitability of motor pathways targeting muscles proximal to the level of interruption of efferents from the CNS. To study the timing of these changes, we have recorded motor evoked potentials (MEPs) in the arm muscles of three normal subjects before, during, and after anesthetic block of the forearm and hand. The amplitudes of MEPs from biceps, which was the muscle immediately proximal to the… CONTINUE READING