Rapid repopulation in radiotherapy: a debate on mechanism. Accelerated repopulation in tumours and normal tissues.

Abstract

Accelerated repopulation is a well established response pattern of normal epithelial to fractionated irradiation. It is delayed until the tissue recognises functional injury. It is well regulated to maintain a steady state and continues until integrity of the tissue is restored. We assume that some of these features of the parental normal tissue are preserved and still operate in squamous cell carcinoma, although probably in a less well controlled and organised manner.

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@article{Trott1991RapidRI, title={Rapid repopulation in radiotherapy: a debate on mechanism. Accelerated repopulation in tumours and normal tissues.}, author={K. R. Trott and Johann Kummermehr}, journal={Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology}, year={1991}, volume={22 3}, pages={159-60} }