Rapid release of entrapped contents from multi-functionalizable, surface cross-linked micelles upon different stimulation.

  title={Rapid release of entrapped contents from multi-functionalizable, surface cross-linked micelles upon different stimulation.},
  author={Shiyong Zhang and Yan Zhao},
  journal={Journal of the American Chemical Society},
  volume={132 31},
  • Shiyong Zhang, Yan Zhao
  • Published 16 July 2010
  • Biology, Chemistry, Materials Science
  • Journal of the American Chemical Society
Hydrophobic guests such as pyrene could be readily trapped inside the micelles of an alkynylated surfactant in the presence of an azide-functionalized cross-linker using the click reaction. The cross-linker was designed to contain cleavable bonds such as geminal diol, disulfide, and acetal. The resulting pyrene-containing water-soluble nanoparticle was under electrostatic stress when diluted below the CMC of the surfactant. Extremely rapid (<1 min) release of the hydrophobic content was… 

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