Rapid processes for purification of capsular polysaccharides from Neisseria meningitidis serogroups A and C.

@article{Sharma2015RapidPF,
  title={Rapid processes for purification of capsular polysaccharides from Neisseria meningitidis serogroups A and C.},
  author={Sandeep Sharma and Sarmad Hanif and Nitin Kumar and Neeraj Joshi and Rakesh Rana and Juned Dalal and Deepti Singh and Manoj Kumar Chhikara},
  journal={Biologicals : journal of the International Association of Biological Standardization},
  year={2015},
  volume={43 5},
  pages={383-9}
}
The glycoconjugate vaccines against Neisseria meningitidis are highly effective, however most of these vaccines are expensive and still out of reach in the developing world as well as the technical know-how and the set-up required for the consistent production of pure polysaccharide is limited. Our laboratory has developed rapid, efficient and scalable processes for the downstream purification of N. meningitidis serogroup A (MenA) and serogroup C (MenC) capsular polysaccharides (PS). The MenC… CONTINUE READING

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