Rapid prenatal detection of down and edwards syndromes by fluorescent polymerase chain reaction with short tandem repeat markers.

@article{Yoon2002RapidPD,
  title={Rapid prenatal detection of down and edwards syndromes by fluorescent polymerase chain reaction with short tandem repeat markers.},
  author={Hye Ryoung Yoon and Yong Seog Park and Young Kee Kim},
  journal={Yonsei medical journal},
  year={2002},
  volume={43 5},
  pages={557-66}
}
Chromosome analysis is the main tool for the prenatal diagnosis of trisomies but requires great technical expertise and time consuming manual procedures. Recently, alternative methods, which provide rapidity and accuracy, without culture, have been developed for pregnant women requiring rapid decisions for termination. In this study, multiplex fluorescent polymerase chain reactions (F-PCRs) were performed by the concurrent use of short tandem repeat (STR) markers specific for the chromosomes 18… CONTINUE READING

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