Rapid periarticular bone loss in rheumatoid arthritis. Possible promotion by normal circulating concentrations of parathyroid hormone or calcitriol (1,25-dihydroxyvitamin D3).

@article{Sambrook1990RapidPB,
  title={Rapid periarticular bone loss in rheumatoid arthritis. Possible promotion by normal circulating concentrations of parathyroid hormone or calcitriol (1,25-dihydroxyvitamin D3).},
  author={Philip N. Sambrook and D. J. Shawe and Richard Hesp and Joan M. Zanelli and Robert McN. Mitchell and Dina R Katz and J. M. Gumpel and Barbara Ansell and Jonathan Reeve},
  journal={Arthritis and rheumatism},
  year={1990},
  volume={33 5},
  pages={
          615-22
        }
}
For approximately 2 years, bone loss was measured in women with early stages of rheumatoid arthritis (RA) and in control subjects, using serial computed tomography and dual photon absorptiometry. Rapid trabecular bone loss from the distal radius was observed in the RA patients but not the controls. The bone loss correlated with initial plasma levels of parathyroid hormone and 1,25-dihydroxyvitamin D3 (calcitriol) concentrations. It has been suggested that these humoral factors may interact with… CONTINUE READING

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