Rapid oscillations in plasma insulin, glucagon, and glucose in obese and normal weight humans.

@article{Hansen1982RapidOI,
  title={Rapid oscillations in plasma insulin, glucagon, and glucose in obese and normal weight humans.},
  author={B. C. Hansen and K C Jen and S Belbez Pek and Robert A. Wolfe},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1982},
  volume={54 4},
  pages={785-92}
}
We have previously identified in fasting monkeys large amplitude, rapid oscillations in plasma levels of insulin, glucagon, and glucose. To determine whether such spontaneous oscillations also occur in man, we studied 9 healthy normal weight subjects and 11 obese volunteers (145-316% ideal body weight). During the morning hours after a 16-h fast, peripheral venous blood was withdrawn at precise 1- or 2-min intervals over 40-120 min. Spectral analysis of the assay results showed significant… CONTINUE READING

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