Rapid on‐site evaluation of fine needle aspiration specimens by cytology scientists: a review of 3032 specimens

  title={Rapid on‐site evaluation of fine needle aspiration specimens by cytology scientists: a review of 3032 specimens},
  author={Paul W. Shield and J. Cosier and G. Ellerby and Michael Gartrell and David J. Papadimos},
To determine: (1) the accuracy of cytology scientists at assessing specimen adequacy by rapid on‐site evaluation (ROSE) at fine needle aspiration (FNA) cytology collections; and (2) whether thyroid FNA with ROSE has lower inadequacy rates than non‐attended FNAs. 

The impact of rapid on‐site evaluation on thyroid fine‐needle aspiration biopsy: A 2‐year cancer center institutional experience

The authors reviewed all thyroid fine‐needle aspiration biopsies performed in their service in recent years to evaluate the impact of ROSE on final adequacy and diagnostic rates.

Adequate at rapid on‐site evaluation (ROSE), but inadequate on final cytologic diagnosis: Analysis of 606 cases of endobronchial ultrasound‐guided trans bronchial needle aspirations (EBUS‐TBNA)

This study analyzes aspirates that were deemed “adequate” on ROSE, but inconclusive upon final cytologic interpretation, to establish a cause-and-effect relationship.

Agreement between rapid on‐site evaluation and the final cytological diagnosis of salivary gland specimens

The aim of the present study was to evaluate agreement and compare accuracy between ROSE and a final cytological diagnosis of salivary gland FNA, using a final histological diagnosis as a gold standard.

Investigation of lymphoid lesions of the head and neck using combined fine needle aspiration cytology and flow cytometry: Accuracy and pitfalls

We reviewed the diagnostic utility of combined fine needle aspiration cytology (FNAC) and flow cytometry (FC) in the diagnosis of lymphoid lesions of the head and neck.

Prospective comparison of cytological specimen adequacy assessment by different rapid staining techniques for rapid on‐site evaluation in fine needle aspiration cytology and their cost‐effectiveness

This study was undertaken as there is sparse literature regarding the best and the most cost‐effective rapid stain.

Utility of endoscopic ultrasound‐guided fine‐needle aspiration cytology in rapid on‐site evaluation for the diagnosis of gastric submucosal tumors: Retrospective analysis of a single‐center experience

The aim of this study was to analyze the utility of EUS‐FNA cytological examination in rapid on‐site evaluation (ROSE) for gastric SMTs.

Use of a low‐cost telecytopathology method for remote assessment of thyroid FNAs

A low‐cost telecytopathology method is analyzed for the remote assessment of thyroid fine‐needle aspiration biopsies (FNABs) with comparison of the primarily rendered adequacy and diagnosis with the final conventional analysis.

Mitotic count of fine needle aspiration material of gastrointestinal stromal tumours of the stomach underestimates actual mitotic count

The relationship between mitotic counts of FNAs and subsequent resections of GISTs of the stomach is examined to determine the utility of this count in fine needle aspiration GIST material.

Factors affecting thyroid nodule fine needle aspiration non‐diagnostic rates: a retrospective association study of 1975 thyroid biopsies

The results from this study demonstrate that thyroid FNAs performed with bedside ROSE can significantly reduce the ND rate compared with non-ROSE, even in experienced groups with low initial ND rates.



Diagnostic accuracy of fine‐needle aspiration biopsy is determined by physician training in sampling technique

The goal of this study was to examine the effects of training physicians in the fine‐needle aspiration sampling‐technique on the diagnostic accuracy of FNAB of palpable breast masses.

Interpretation of the Paucicellular Thyroid Fine Needle Aspiration Biopsy Specimen

The author presents a case illustrating a common pitfall in FNA interpretation, which is a common source of error, in the evaluation of thyroid nodules.

Ultrasound guidance improves the adequacy of our preoperative thyroid cytology but not its accuracy

The results of freehand FNA and USS‐guided core samples for cytology in two separate patient groups in a centre for thyroid cytology are presented.

Diagnostic value and cost‐effectiveness of on‐site evaluation of fine‐needle aspiration specimens: Review of 5,688 cases

On‐site cytopathologic evaluation of FNA specimens is accurate, cost‐effective, and has improved patient care at the institution and could be realized by utilizing on‐site evaluation despite the additional fee due to a higher rate of specimen adequacy.

The impact of assessing specimen adequacy and number of needle passes for fine-needle aspiration biopsy of thyroid nodules.

It is concluded that US-guided FNAB with onsite evaluation of cytology specimens substantially increases the adequacy of cytological specimens and decreases the number of required needle passes, which ultimately reduces patient discomfort and diagnostic errors, thus raising the question as to whether this should eventually become the standard of care.

Improved laboratory resource utilization and patient care with the use of rapid on‐site evaluation for endobronchial ultrasound fine‐needle aspiration biopsy

This study examines EBUS FNA biopsy procedures with and without ROSE, and investigates the impact of ROSE service on the EBUS procedure and laboratory resource utilization.

Cytotechnologist-attended on-site adequacy evaluation of thyroid fine-needle aspiration: comparison with cytopathologists and correlation with the final interpretation.

The results indicate that the accuracy of cytotechnologists is comparable with that of cytopathologists in conducting OSEA of the thyroid, and subadequate specimens had a higher rate of indeterminate diagnosis.

The role of immediate cytological evaluation in CT-guided biopsy.

Cost-effectiveness of immediate specimen adequacy assessment of thyroid fine-needle aspirations.

It may be most cost-effective to routinely obtain 3 passes and to perform immediate adequacy assessment of thyroid fine-needle aspirations under special circumstances such as repeated procedures.

Ultrasound-Guided Fine Needle Aspiration Biopsy of Thyroid Nodules

The role of ultrasound-guided fine needle aspiration (UG FNA) in the diagnosis of thyroid nodules is reviewed, which is often valuable, and sometimes essential, in obtaining accurate diagnostic material.