Rapid noninvasive optical imaging of tissue composition in breast tumor margins.

@article{Wilke2009RapidNO,
  title={Rapid noninvasive optical imaging of tissue composition in breast tumor margins.},
  author={Lee Gravatt Wilke and J. Quincy Brown and Torre M Bydlon and Stephanie A L Kennedy and Lisa M. Richards and Marlee K. Junker and Jennifer E. Gallagher and William T. Barry and Joseph Geradts and Nimmi Ramanujam},
  journal={American journal of surgery},
  year={2009},
  volume={198 4},
  pages={566-74}
}
BACKGROUND In women undergoing breast conserving surgery (BCS), up to 60% can require re-excision. Our objective is to develop an optically based technology which can differentiate benign from malignant breast tissues intraoperatively through differences in tissue composition factors. METHODS A prospective study of optical imaging of BCS margins is being performed. Optical images are transformed into tissue composition maps with parameters of total hemoglobin concentration, b-carotene… CONTINUE READING

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