Rapid monitoring of immune reconstitution after allogeneic stem cell transplantation--a comparison of different assays for the detection of cytomegalovirus-specific T cells.

@article{AbuKhader2013RapidMO,
  title={Rapid monitoring of immune reconstitution after allogeneic stem cell transplantation--a comparison of different assays for the detection of cytomegalovirus-specific T cells.},
  author={Ahmad Abu-Khader and S Krause},
  journal={European journal of haematology},
  year={2013},
  volume={91 6},
  pages={534-45}
}
OBJECTIVES Cytotoxic T cells (CTLs) play an important role in controlling cytomegalovirus (CMV) infection after allogeneic hematopoietic stem cell transplantation (HSCT). The purpose of this study was to compare four different assays to detect CMV antigen-specific T cells for the monitoring of CMV-specific immune reconstitution after HSCT. METHODS Comparative monitoring of CMV-specific T cells was performed using HLA tetramer, interferon-gamma enzyme-linked immunospot (ELISPOT), intracellular… CONTINUE READING

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