Rapid modulation of electrolyte transport in Caco-2 cell monolayers by enteropathogenic Escherichia coli (EPEC) infection.

@article{Collington1998RapidMO,
  title={Rapid modulation of electrolyte transport in Caco-2 cell monolayers by enteropathogenic Escherichia coli (EPEC) infection.},
  author={G K Collington and Ian Westerby Booth and Stuart Knutton},
  journal={Gut},
  year={1998},
  volume={42 2},
  pages={200-7}
}
BACKGROUND AND AIMS The pathophysiology of enteropathogenic Escherichia coli (EPEC) diarrhoea remains uncertain. EPEC adhere to enterocytes and transduce signals which produce a characteristic "attaching and effacing" (A/E) lesion in the brush border membrane. The present in vitro study was designed to determine whether signal transduction by EPEC also influences electrolyte transport. METHODS Caco-2 cell monolayers were rapidly infected with wild type EPEC strain E2348/69, or the signal… CONTINUE READING