Rapid modulation of GABA in sensorimotor cortex induced by acute deafferentation.

@article{Levy2002RapidMO,
  title={Rapid modulation of GABA in sensorimotor cortex induced by acute deafferentation.},
  author={Lucien Levy and Ulf Ziemann and Robert Chen and Leonardo G. Cohen},
  journal={Annals of neurology},
  year={2002},
  volume={52 6},
  pages={755-61}
}
Recovery of function after acute injury to the central nervous system may be controlled by the availability of gamma-aminobutyric acid (GABA), the main inhibitory neurotransmitter in the cerebral cortex. Acute lesions as well as manipulation of sensory inputs can lead to rapid reorganization of the cerebral cortex, occurring within minutes to hours. Reduction of cortical inhibitory tone through a decrease in the availability of GABA has been suggested as a possible mechanism; however, the… CONTINUE READING

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