Rapid mineralization of electrospun scaffolds for bone tissue engineering.

@article{Andric2011RapidMO,
  title={Rapid mineralization of electrospun scaffolds for bone tissue engineering.},
  author={Tea Andric and Lee D Wright and Joseph Freeman},
  journal={Journal of biomaterials science. Polymer edition},
  year={2011},
  volume={22 11},
  pages={1535-50}
}
We investigated different techniques to enhance calcium phosphate mineral precipitation onto electrospun poly((L)-lactide) (PLLA) scaffolds when incubated in concentrated simulated body fluid (SBF), 10×SBF. The techniques included the use of vacuum, pre-treatment with 0.1 M NaOH and electrospinning gelatin/PLLA blends as means to increase overall mineral precipitation and distribution throughout the scaffolds. Mineral precipitation was evaluated using environmental scanning electron microscopy… CONTINUE READING