Rapid lamina propria retraction and zipper-like constriction of the epithelium preserves the epithelial lining in human small intestine exposed to ischaemia-reperfusion.

@article{Grootjans2011RapidLP,
  title={Rapid lamina propria retraction and zipper-like constriction of the epithelium preserves the epithelial lining in human small intestine exposed to ischaemia-reperfusion.},
  author={Joep Grootjans and Geertje Thuijls and Joep Pm Derikx and Ronald M. van Dam and Cornelis H. C. Dejong and Wim A. Buurman},
  journal={The Journal of pathology},
  year={2011},
  volume={224 3},
  pages={411-9}
}
To ensure a sufficient barrier between a host and noxious luminal content, the intestinal epithelium must be equipped with efficient mechanisms to limit damage to the epithelial lining. Using a human model, we were able to investigate these mechanisms in the human gut exposed to ischaemia-reperfusion (IR) over the time course of 150 min. In 10 patients a… CONTINUE READING