Rapid kinetic measurements of second messenger formation in olfactory cilia from channel catfish.

@article{Restrepo1993RapidKM,
  title={Rapid kinetic measurements of second messenger formation in olfactory cilia from channel catfish.},
  author={Diego Restrepo and Ingrid Boekhoff and Heinz Breer},
  journal={The American journal of physiology},
  year={1993},
  volume={264 4 Pt 1},
  pages={C906-11}
}
The effect of stimulating olfactory cilia from the channel catfish (Ictalurus punctatus) with odorant amino acids on the formation of adenosine 3',5'-cyclic monophosphate, guanosine 3',5'-cyclic monophosphate, and inositol 1,4,5-trisphosphate (IP3) was studied in the subsecond time scale using a quenched flow technique. L-Alanine (L-Ala) and L-cysteine (L-Cys) (100 microM) elicited a transient elevation in IP3 levels that peaked at 25 ms. In contrast, even at high concentration a mixture of… CONTINUE READING
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