Rapid infusion of a loading dose of intravenous levetiracetam with minimal dilution: a safety study.

@article{Wheless2009RapidIO,
  title={Rapid infusion of a loading dose of intravenous levetiracetam with minimal dilution: a safety study.},
  author={James W. Wheless and Dave Clarke and Collin A. Hovinga and Michelle Ellis and Misha Durmeier and Amy L. McGregor and F. Frederick Perkins},
  journal={Journal of child neurology},
  year={2009},
  volume={24 8},
  pages={946-51}
}
Intravenous antiepileptic drugs are required in patients needing urgent treatment or unable to take oral medication. The safety of intravenous levetiracetam has been established in prospective studies of adult epilepsy and healthy participants. The authors performed a prospective, single-center study to evaluate the safety of a rapid loading dose of intravenous levetiracetam. Patients were divided into 3 equal dosing groups (N = 15 each): 20, 40, and 60 mg/kg (corresponding to maximum doses of… CONTINUE READING