Rapid induction of specific associative behavioral memory by stimulation of the nucleus basalis in the rat.

@article{Miasnikov2006RapidIO,
  title={Rapid induction of specific associative behavioral memory by stimulation of the nucleus basalis in the rat.},
  author={Alexandre A Miasnikov and Jemmy C Chen and Norman M. Weinberger},
  journal={Neurobiology of learning and memory},
  year={2006},
  volume={86 1},
  pages={47-65}
}
Hypothesized circuitry enabling behavioral memory formation can be tested by its direct activation in the absence of normal experience. Neuromodulation via the cortical release of acetylcholine by the nucleus basalis (NB) is hypothesized to be sufficient to induce specific, associative behavioral memory. Previously, we found that tone paired with stimulation of the nucleus basalis (NBs) for 3000 trials over 15 days induced such memory, supporting the hypothesis. However, as standard associative… CONTINUE READING
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