Corpus ID: 24989796

Rapid induction of seven proteins in human lymphocytes by interferon; correlation to natural killer cell activity.

@article{Gustafsson1982RapidIO,
  title={Rapid induction of seven proteins in human lymphocytes by interferon; correlation to natural killer cell activity.},
  author={A. Gustafsson and S. Sundstr{\"o}m and T. Ny and E. Lundgren},
  journal={Journal of immunology},
  year={1982},
  volume={129 5},
  pages={
          1952-9
        }
}
  • A. Gustafsson, S. Sundström, +1 author E. Lundgren
  • Published 1982
  • Biology, Medicine
  • Journal of immunology
  • The early effects of interferon (IFN) on the synthesis of protein in human nylon wool-nonadherent lymphocytes have been stimulated by use of two-dimensional electrophoresis. IFN-alpha or -beta as well as Escherichia coli-produced IFN-alpha 2 induced the rapid formation of seven proteins (Mr 80, 75, 62, 53, 38, 36, and 33 kD). At least five proteins were expressed within 2 hr of incubation with IFN. The synthesis of the seven proteins seemed to require rapid transcription of new RNA, because… CONTINUE READING
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