Rapid increase in clusters of presynaptic proteins at onset of long-lasting potentiation.

@article{Antonova2001RapidII,
  title={Rapid increase in clusters of presynaptic proteins at onset of long-lasting potentiation.},
  author={Irina Antonova and Ottavio Arancio and A C Trillat and Hong-gang Wang and Leonard Zablow and Hiroshi Udo and Eric R Kandel and R. David Hawkins},
  journal={Science},
  year={2001},
  volume={294 5546},
  pages={1547-50}
}
A change in the efficiency of synaptic communication between neurons is thought to underlie learning. Consistent with recent studies of such changes, we find that long-lasting potentiation of synaptic transmission between cultured hippocampal neurons is accompanied by an increase in the number of clusters of postsynaptic glutamate receptors containing the subunit GluR1. In addition, potentiation is accompanied by a rapid and long-lasting increase in the number of clusters of the presynaptic… CONTINUE READING
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