Rapid in vivo induction of leukocyte tissue factor mRNA and protein synthesis following low dose endotoxin administration to rabbits.

Abstract

INTRODUCTION Disseminated intravascular coagulation in humans is frequently associated with Gram-negative bacterial sepsis. Therefore, to examine the role and time frame of the in vivo induction of tissue factor (TF) by bacterial endotoxin, a reverse transcription polymerase chain reaction and a solid-phase ELISA assay were developed to monitor the in vivo… (More)

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@article{Brutzki2001RapidIV, title={Rapid in vivo induction of leukocyte tissue factor mRNA and protein synthesis following low dose endotoxin administration to rabbits.}, author={T C Brutzki and Myron Kulczycky and Leslie Bardossy and Bryan J. Clarke and Morris A. Blajchman}, journal={The hematology journal : the official journal of the European Haematology Association}, year={2001}, volume={2 3}, pages={188-95} }