Rapid hydrogenation of unsaturated sterols and bile alcohols using microwaves.

@article{Dayal1997RapidHO,
  title={Rapid hydrogenation of unsaturated sterols and bile alcohols using microwaves.},
  author={Bishambar Dayal and Norman H. Ertel and K R Rapole and A Asgaonkar and Gerald Salen},
  journal={Steroids},
  year={1997},
  volume={62 5},
  pages={451-4}
}
This paper describes an operationally simple, rapid hydrogenation of unsaturated sterols and bile alcohols in a domestic microwave oven. This has been achieved by the addition of catalytic amounts of Pd/C in methylene chloride/propylene glycol solvents in the presence of ammonium formate followed by microwave irradiation. It is suggested that this methodology will be helpful in the identification of saturated and unsaturated sterols with different side-chain structures in rare diseases… CONTINUE READING