Rapid genotypic detection of rifampin- and isoniazid-resistant Mycobacterium tuberculosis directly in clinical specimens.

@article{Bang2006RapidGD,
  title={Rapid genotypic detection of rifampin- and isoniazid-resistant Mycobacterium tuberculosis directly in clinical specimens.},
  author={Didi Bang and Ase Beng{\aa}rd Andersen and Vibeke \Ostergaard Thomsen},
  journal={Journal of clinical microbiology},
  year={2006},
  volume={44 7},
  pages={2605-8}
}
A multiplex PCR DNA strip assay (Genotype MTBDR) designed to detect rifampin (rpoB) and high-level isoniazid (katG) resistance mutations in Mycobacterium tuberculosis isolates was optimized for clinical specimens. Successful genotypic results were achieved with 36 of 38 (95%) smear-positive respiratory specimens, allowing rapid therapeutic adjustments in transmittable drug-resistant tuberculosis. 

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Susceptibility testing of mycobacteria , nocardiae , and other aerobic actinomycetes

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