Rapid epithelial-sheet sealing in the Caenorhabditis elegans embryo requires cadherin-dependent filopodial priming

@article{Raich1999RapidES,
  title={Rapid epithelial-sheet sealing in the Caenorhabditis elegans embryo requires cadherin-dependent filopodial priming},
  author={William B. Raich and Cristina Agbunag and Jeff Hardin},
  journal={Current Biology},
  year={1999},
  volume={9},
  pages={1139-S1}
}
BACKGROUND During embryonic development, epithelia with free edges must join together to create continuous tissues that seal the interior of the organism from the outside environment; failure of epithelial sealing underlies several common human birth defects. Sealing of epithelial sheets in embryos can be extremely rapid, dramatically exceeding the rate of adherens junction formation by epithelial cells in culture or during healing of epithelial wounds. Little is known about the dynamic… CONTINUE READING
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