Rapid elevation of gentamicin levels in the human labyrinth following intravenous administration.

Abstract

HYPOTHESIS Adequate quantities of labyrinthine fluid can be sampled from the human labyrinth to perform quantitative analysis of medications. A rapid elevation of intralabyrinthine gentamicin levels after intravenous administration can be measured. A model for the sampling of human inner ear fluid in this manner is described. BACKGROUND The risk of… (More)

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