Rapid diagnosis of active tuberculosis by detecting antibodies from lymphocyte secretions.

  title={Rapid diagnosis of active tuberculosis by detecting antibodies from lymphocyte secretions.},
  author={Rubhana Raqib and Jubayer Rahman and A K M Kamaluddin and S. M. Mostafa Kamal and Fauzia A Banu and Shakeel Ahmed and Zeaur Rahim and Pradip Kumar Bardhan and Jan Olof Andersson and David A Sack},
  journal={The Journal of infectious diseases},
  volume={188 3},
In the present study, we investigated the tuberculosis (TB) diagnostic performance of an assay on the basis of detection of TB-specific antibodies from peripheral blood mononuclear cells (PBMCs), to determine whether antibodies in lymphocyte secretions obtained from PBMCs would better reflect active disease than antibodies in serum. PBMCs from patients with and without TB cultured in various concentrations for different times were assessed. Immunoglobulin G (IgG) specific for antigen (bacille… CONTINUE READING

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