Rapid development of cardiac dysfunction in a canine model of insulin resistance and moderate obesity

@article{Broussard2015RapidDO,
  title={Rapid development of cardiac dysfunction in a canine model of insulin resistance and moderate obesity},
  author={Josiane L. Broussard and Michael D Nelson and Cathryn M Kolka and Isaac Asare Bediako and Rebecca L. Paszkiewicz and Laura Smith and Edward W. Szczepaniak and Darko Stefanovski and Lidia S. Szczepaniak and Richard N Bergman},
  journal={Diabetologia},
  year={2015},
  volume={59},
  pages={197-207}
}
The worldwide incidence of obesity and diabetes continues to rise at an alarming rate. A major cause of the morbidity and mortality associated with obesity and diabetes is heart disease, yet the mechanisms that lead to cardiovascular complications remain unclear. We performed cardiac MRI to assess left ventricular morphology and function during the development of moderate obesity and insulin resistance in a well-established canine model (n = 26). To assess the influence of dietary fat… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 9 times over the past 90 days. VIEW TWEETS

References

Publications referenced by this paper.
Showing 1-10 of 48 references

insights into subclinical ventricular dysfunction

  • MM Barbosa, AM Beleigoli, M de Fatima Diniz, CV Freire, AL Ribeiro, obesity Nunes MC Strain imaging in morbid
  • Clin Cardiol 34:288–293 Diabetologia
  • 2016

Similar Papers

Loading similar papers…