Rapid detection of vancomycin-resistant enterococci from rectal swabs by the Cepheid Xpert vanA/vanB assay.

@article{Bourdon2010RapidDO,
  title={Rapid detection of vancomycin-resistant enterococci from rectal swabs by the Cepheid Xpert vanA/vanB assay.},
  author={Nancy Bourdon and Rapha{\"e}l B{\'e}renger and Romain Lepoultier and Audrey Mouet and Claire Lesteven and France Borgey and Marguerite Fines-Guyon and Roland Leclercq and Vincent Cattoir},
  journal={Diagnostic microbiology and infectious disease},
  year={2010},
  volume={67 3},
  pages={291-3}
}
The detection of vancomycin-resistant enterococci using a novel commercial multiplex real-time polymerase chain reaction assay (Xpert vanA/vanB, Cepheid, Sunnyvale, CA) was evaluated on 804 rectal swab specimens. Compared to enriched culture, sensitivity and negative predictive value of this method were 100%. Many false-positive results were recovered (sensitivity, 85.4%; positive predictive value, 8.7%), especially for the vanB gene. 

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