Rapid detection of Mycobacterium tuberculosis biomarkers in a sandwich immunoassay format using a waveguide-based optical biosensor.

Abstract

Early diagnosis of active tuberculosis (TB) remains an elusive challenge, especially in individuals with disseminated TB and HIV co-infection. Recent studies have shown a promise for the direct detection of pathogen-specific biomarkers such as lipoarabinomannan (LAM) for the diagnosis of TB in HIV-positive individuals. Currently, traditional immunoassay… (More)
DOI: 10.1016/j.tube.2012.05.009

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Cite this paper

@article{Mukundan2012RapidDO, title={Rapid detection of Mycobacterium tuberculosis biomarkers in a sandwich immunoassay format using a waveguide-based optical biosensor.}, author={Harshini Mukundan and Sandeep Kumar and Dominique N. Price and Sonja M Ray and Ye-Jin Lee and Seonyeong Min and Seokyong Eum and Jessica Z. Kubicek-Sutherland and Jesse M Resnick and W. Kevin Grace and Aaron S. Anderson and Soo Hee Hwang and Sang - Nae Cho and Laura E. Via and Clifton Earl Barry and Ramamurthy Sakamuri and Basil I. Swanson}, journal={Tuberculosis}, year={2012}, volume={92 5}, pages={407-16} }