Rapid detection of Candida albicans in clinical samples by DNA amplification of common regions from C. albicans-secreted aspartic proteinase genes.

@article{Flahaut1998RapidDO,
  title={Rapid detection of Candida albicans in clinical samples by DNA amplification of common regions from C. albicans-secreted aspartic proteinase genes.},
  author={Marjorie Flahaut and Dominique Sanglard and Michel Monod and Jacques Bille and M{\'e}lanie Rossier},
  journal={Journal of clinical microbiology},
  year={1998},
  volume={36 2},
  pages={395-401}
}
Laboratory diagnosis based on genomic amplification methods such as PCR may provide an alternative and more sensitive method than conventional culture for the early detection of deep-seated candidiasis, an increasing cause of morbidity and mortality among immunocompromised patients. A novel method of DNA extraction from clinical samples based on treatment with proteinase K and isolation of DNA on a silica membrane was developed. The targets used for DNA amplification were the Candida albicans… CONTINUE READING

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