Rapid dendritic cell recruitment is a hallmark of the acute inflammatory response at mucosal surfaces

  title={Rapid dendritic cell recruitment is a hallmark of the acute inflammatory response at mucosal surfaces},
  author={Andrew S. McWilliam and Delia Jane Nelson and Jennifer A. Thomas and Patrick G. Holt},
  journal={The Journal of Experimental Medicine},
  pages={1331 - 1336}
Immunohistochemical analysis of challenge sites such as skin and the peritoneal cavity has identified neutrophils as virtually the sole cellular participants in acute bacterial inflammation, peak influx occurring 24-48 h in advance of mononuclear cell populations associated with adaptive immunity. This study challenges the general applicability of this paradigm. We demonstrate here that the earliest detectable cellular response after inhalation of Moraxella catarrhalis organisms is the… CONTINUE READING

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