Rapid degradation of polyadenylated oop RNA.

  title={Rapid degradation of polyadenylated oop RNA.},
  author={Agnieszka Szalewska-Pałasz and Borys Wr{\'o}bel and Grzegorz Węgrzyn},
  journal={FEBS letters},
  volume={432 1-2},
The oop RNA is a short (77 nucleotides (nt)) transcript encoded by bacteriophage lambda which acts as an antisense RNA for lambda cII gene expression. Recently we demonstrated that oop RNA is specifically polyadenylated at its 3' end by poly(A) polymerase I (PAP I), the pcnB gene product. Here we demonstrate that the half life of oop RNA is 3 times longer in the pcnB mutant relative to the pcnB+ host, indicating that polyadenylation of this transcript causes its accelerated degradation… CONTINUE READING