Rapid declines in total lymphocyte counts and hemoglobin concentration prior to AIDS among HIV-1-infected men.

@article{Lau2003RapidDI,
  title={Rapid declines in total lymphocyte counts and hemoglobin concentration prior to AIDS among HIV-1-infected men.},
  author={Bryan Lau and Stephen J Gange and John P. Phair and Sharon A. Riddler and Roger Detels and Joseph B. Margolick},
  journal={AIDS},
  year={2003},
  volume={17 14},
  pages={2035-44}
}
OBJECTIVE To describe temporal patterns in total lymphocyte count (TLC) and hemoglobin (Hgb) concentration during HIV infection and relate these patterns to changes in other markers and to clinical disease. DESIGN Prospective cohort study. METHODS Longitudinal trajectories of total lymphocyte count and hemoglobin from men in the Multicenter AIDS Cohort Study were studied by applying, to each individual, a segmented regression model to capture changes in marker trajectories at an inflection… CONTINUE READING