Rapid decline of kidney function increases cardiovascular risk in the elderly.

  title={Rapid decline of kidney function increases cardiovascular risk in the elderly.},
  author={Michael G. Shlipak and Ronit Katz and Bryan R Kestenbaum and David S Siscovick and Linda F. Fried and Anne B. Newman and Dena E Rifkin and Mark J Sarnak},
  journal={Journal of the American Society of Nephrology : JASN},
  volume={20 12},
Chronic kidney disease (CKD), defined at a specific time point, is an important risk factor for cardiovascular disease. Whether the rate of kidney function decline contributes additional cardiovascular risk is unknown. In the Cardiovascular Health Study, we compared the associations of changes in kidney function during the first 7 yr with the incidence of heart failure (HF), myocardial infarction (MI), stroke, and peripheral arterial disease (PAD) during the subsequent 8 yr. We defined a rapid… CONTINUE READING
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