Rapid clearance of Lyme disease spirochetes lacking OspC from skin.

@article{Tilly2007RapidCO,
  title={Rapid clearance of Lyme disease spirochetes lacking OspC from skin.},
  author={Kit Tilly and Aaron C Bestor and Mollie W Jewett and Patricia A Rosa},
  journal={Infection and immunity},
  year={2007},
  volume={75 3},
  pages={1517-9}
}
We previously demonstrated that Borrelia burgdorferi requires OspC to colonize a mammalian host. To delineate this requirement, we analyzed the clearance of ospC mutant spirochetes and found that they were eliminated within 48 h. We conclude that B. burgdorferi uses OspC to resist innate host defenses immediately after transmission. 
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