Rapid blood pressure control with minoxidil: acute and chronic effects on blood pressure, sodium excretion, and the renin-aldosterone system.

@article{Grim1979RapidBP,
  title={Rapid blood pressure control with minoxidil: acute and chronic effects on blood pressure, sodium excretion, and the renin-aldosterone system.},
  author={Clarence E. Grim and Friedrich C. Luft and Carlene M Grim and Paul E. Klotman and J W Van Huysse and Myron H. Weinberger},
  journal={Archives of internal medicine},
  year={1979},
  volume={139 5},
  pages={529-33}
}
Changes in blood pressure, heart rate, electrolyte excretion, and the renin-angiotensin-aldosterone system were monitored before and after minoxidil was added to a regimen of a diuretic and propranolol hydrochloride in 12 severely hypertensive patients. None required more than 40 mg of minoxidil daily for control. On a constant intake, urinary sodium excretion decreased, while urinary potassium excretion remained stable. Heart rate, body weight, and plasma volume increased, while creatinine… CONTINUE READING
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